Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.
After being banned for 10 years from a local drinking competition appropriately named "Flipadelphia," the gang tries to reignite their old rivalry with another local bar. Finding that they are in need of some serious practice, the guys head to Dennis' old fraternity house at the University of Pennsylvania to get their game up to speed while Dee hones her skills on her own. Frank wears skinny pants.